Fatigue Clinical Trials: Medline
Barsevick AM, Dudley W, Beck S, Sweeney C, Whitmer K, Nail L. A randomized
clinical trial of energy conservation for patients with cancer-related fatigue.
Cancer. 2004 Mar 15;100(6):1302-10.
Bennett JA, Lyons KS, Winters-Stone K, Nail LM, Scherer J. Motivational
interviewing to increase physical activity in long-term cancer survivors: a
randomized controlled trial. Nurs Res. 2007 Jan-Feb;56(1):18-27.
Berndt E, Kallich J, McDermott A, Xu X, Lee H, Glaspy J. Reductions in
anaemia and fatigue are associated with improvements in productivity in cancer
patients receiving chemotherapy. Pharmacoeconomics. 2005;23(5):505-14.
Bower JE, Ganz PA, Dickerson SS, Petersen L, Aziz N, Fahey JL. Diurnal
cortisol rhythm and fatigue in breast cancer survivors. Psychoneuroendocrinology.
Brown P, Clark MM, Atherton P, Huschka M, Sloan JA, Gamble G, Girardi J, Frost
MH, Piderman K, Rummans TA. Will improvement in quality of life (QOL) impact
fatigue in patients receiving
radiation therapy for advanced cancer? Am J Clin Oncol. 2006 Feb;29(1):52-8.
Butler L, Bacon M, Carey M, Zee B, Tu D, Bezjak A. Determining the
relationship between toxicity and quality of life in an ovarian cancer
chemotherapy clinical trial. J Clin Oncol. 2004 Jun 15;22(12):2461-8.
Campbell A, Mutrie N, White F, McGuire F, Kearney N. A pilot study of a
supervised group exercise programme as a rehabilitation treatment for women with
breast cancer receiving adjuvant treatment. Eur J Oncol Nurs. 2005
Carlson LE, Smith D, Russell J, Fibich C, Whittaker T. Individualized
exercise program for the treatment of severe fatigue in patients after
allogeneic hematopoietic stem-cell transplant: a pilot study. Bone Marrow
Transplant. 2006 May;37(10):945-54.
Cella D, Kallich J, McDermott A, Xu X. The longitudinal relationship of
hemoglobin, fatigue and quality of life in anemic cancer patients: results from
five randomized clinical trials. Ann Oncol. 2004 Jun;15(6):979-86.
Clark M, Isaacks-Downton G, Wells N, Redlin-Frazier S, Eck C, Hepworth JT,
Chakravarthy B. Use of preferred music to reduce emotional distress and
symptom activity during radiation therapy. J Music Ther. 2006 Fall;43(3):247-65.
Cortesi E, Gascon P, Henry D, Littlewood T, Milroy R, Pronzato P, Reinhardt U,
Shasha D, Thatcher N, Wilkinson P. Standard of care for cancer-related
anemia: improving hemoglobin levels and quality of life. Oncology. 2005;68 Suppl
Culos-Reed SN, Carlson LE, Daroux LM, Hately-Aldous S. A pilot study of yoga
for breast cancer survivors: physical and psychological benefits. Psychooncology.
Deng G, Cassileth BR, Yeung KS. Complementary therapies for cancer-related
symptoms. J Support Oncol. 2004 Sep-Oct;2(5):419-26; discussion 427-9. Review.
Duncan GG, Epstein JB, Tu D, El Sayed S, Bezjak A, Ottaway J, Pater J; National
Cancer Institute of Canada Clinical Trials Group. Quality of life,
mucositis, and xerostomia from radiotherapy for head and neck cancers: a report
from the NCIC CTG HN2 randomized trial of an antimicrobial lozenge to prevent
mucositis. Head Neck. 2005 May;27(5):421-8.
Elam JL, Carpenter JS, Shu XO, Boyapati S, Friedmann-Gilchrist J.
Methodological issues in the investigation of ginseng as an intervention for
fatigue. Clin Nurse Spec. 2006 Jul-Aug;20(4):183-9.
Fernandes R, Stone P, Andrews P, Morgan R, Sharma S. Comparison between
fatigue, sleep disturbance, and circadian rhythm in cancer inpatients and
healthy volunteers: evaluation of diagnostic criteria for cancer-related
fatigue. J Pain Symptom Manage. 2006 Sep;32(3):245-54.
Gielissen MF, Verhagen S, Witjes F, Bleijenberg G. Effects of cognitive
behavior therapy in severely fatigued disease-free cancer patients compared with
patients waiting for cognitive behavior therapy: a randomized controlled trial.
J Clin Oncol. 2006 Oct 20;24(30):4882-7.
Given BA, Given CW, Jeon S, Sikorskii A. Effect of neutropenia on the impact
of a cognitive-behavioral intervention for symptom management. Cancer. 2005 Aug
Hartvig P, Aulin J, Wallenberg S, Wagenius G. Physical exercise for
cytotoxic drug-induced fatigue.
J Oncol Pharm Pract. 2006 Dec;12(4):183-91.
Hewitt JA, Mokbel K, van Someren KA, Jewell AP, Garrod R. Exercise for
breast cancer survival: the effect on cancer risk and cancer-related fatigue (CRF).
Int J Fertil Womens Med. 2005 Sep-Oct;50(5 Pt 1):231-9. Review.
Hoekstra J, de Vos R, van Duijn NP, Schade E, Bindels PJ. Using the symptom
monitor in a randomized controlled trial: the effect on symptom prevalence and
severity. J Pain Symptom Manage. 2006 Jan;31(1):22-30.
Houborg KB, Jensen MB, Rasmussen P, Gandrup P, Schroll M, Laurberg S.
Postoperative physical training following colorectal surgery: a randomised,
placebo-controlled study. Scand J Surg. 2006;95(1):17-22.
Jean-Pierre P, Mustian K, Kohli S, Roscoe JA, Hickok JT, Morrow GR.
Community-based clinical oncology research trials for cancer-related fatigue. J
Support Oncol. 2006 Nov-Dec;4(10):511-6. Review.
Kallich J, McDermott A, Xu X, Fayers P, Cella D. The relationship between
patient knowledge of hemoglobin levels and health-related quality of life. Qual
Life Res. 2006 Feb;15(1):57-68.
Kim Y, Hickok JT, Morrow G. Fatigue and depression in cancer patients
undergoing chemotherapy: an emotion approach. J Pain Symptom Manage. 2006
Kohara H, Miyauchi T, Suehiro Y, Ueoka H, Takeyama H, Morita T. Combined
modality treatment of aromatherapy, footsoak, and reflexology relieves fatigue
in patients with cancer. J Palliat Med. 2004 Dec;7(6):791-6.
Lai JS, Cella D, Dineen K, Bode R, Von Roenn J, Gershon RC, Shevrin D. An
item bank was created to improve the measurement of cancer-related fatigue. J
Clin Epidemiol. 2005 Feb;58(2):190-7.
Littlewood TJ, Kallich JD, San Miguel J, Hendricks L, Hedenus M. Efficacy of
darbepoetin alfa in alleviating fatigue and the effect of fatigue on quality of
life in anemic patients with lymphoproliferative malignancies. J Pain Symptom
Manage. 2006 Apr;31(4):317-25.
Losito J, Murphy S, Thomas M. The effects of group exercise on fatigue and
quality of life during cancer treatment. Oncol Nurs Forum. 2006 Jul
Monk JP, Phillips G, Waite R, Kuhn J, Schaaf LJ, Otterson GA, Guttridge D,
Rhoades C, Shah M, Criswell T, Caligiuri MA, Villalona-Calero MA. Assessment
of tumor necrosis factor alpha blockade as an intervention to improve
tolerability of dose-intensive chemotherapy in cancer patients. J Clin Oncol.
2006 Apr 20;24(12):1852-9.
Morrow GR, Hickok JT, Roscoe JA, Raubertas RF, Andrews PL, Flynn PJ, Hynes HE,
Banerjee TK, Kirshner JJ, King DK; University of Rochester Cancer Center
Community Clinical Oncology Program.
Differential effects of paroxetine on fatigue and depression: a randomized,
double-blind trial from the University of Rochester Cancer Center Community
Clinical Oncology Program. J Clin Oncol. 2003 Dec 15;21(24):4635-41.
Moss EL, Simpson JS, Pelletier G, Forsyth P. An open-label study of the
effects of bupropion SR on fatigue, depression and quality of life of mixed-site
cancer patients and their partners. Psychooncology. 2006 Mar;15(3):259-67.
O'Shaughnessy JA, Vukelja SJ, Holmes FA, Savin M, Jones M, Royall D, George M,
Von Hoff D. Feasibility of quantifying the effects of epoetin alfa therapy
on cognitive function in women with breast cancer undergoing adjuvant or
neoadjuvant chemotherapy. Clin Breast Cancer. 2005 Feb;5(6):439-46.
Pinto BM, Frierson GM, Rabin C, Trunzo JJ, Marcus BH. Home-based physical
activity intervention for breast cancer patients. J Clin Oncol. 2005 May
Ream E, Richardson A, Alexander-Dann C. Supportive intervention for fatigue
in patients undergoing chemotherapy: a randomized controlled trial. J Pain
Symptom Manage. 2006 Feb;31(2):148-61.
Roscoe JA, Matteson SE, Mustian KM, Padmanaban D, Morrow GR. Treatment of
radiotherapy-induced fatigue through a nonpharmacological approach. Integr
Cancer Ther. 2005 Mar;4(1):8-13.
Roscoe JA, Morrow GR, Hickok JT, Mustian KM, Griggs JJ, Matteson SE, Bushunow P,
Qazi R, Smith B. Effect of paroxetine hydrochloride (Paxil) on fatigue and
depression in breast cancer patients receiving chemotherapy. Breast Cancer Res
Treat. 2005 Feb;89(3):243-9.
Savard J, Simard S, Ivers H, Morin CM. Randomized study on the efficacy of
cognitive-behavioral therapy for insomnia secondary to breast cancer, part I:
Sleep and psychological effects. J Clin Oncol. 2005 Sep 1;23(25):6083-96.
Savonije JH, van Groeningen CJ, Wormhoudt LW, Giaccone G. Early Intervention
with epoetin alfa during platinum-based chemotherapy: an analysis of
quality-of-life results of a multicenter, randomized, controlled trial compared
with population normative data. Oncologist. 2006 Feb;11(2):197-205.
Savonije JH, van Groeningen CJ, Wormhoudt LW, Giaccone G. Early intervention
with epoetin alfa during platinum-based chemotherapy: an analysis of the results
of a multicenter, randomized, controlled trial based on initial hemoglobin
level. Oncologist. 2006 Feb;11(2):206-16.
Sherwood P, Given BA, Given CW, Champion VL, Doorenbos AZ, Azzouz F, Kozachik S,
Wagler-Ziner K, Monahan PO. A cognitive behavioral intervention for symptom
management in patients with advanced cancer. Oncol Nurs Forum. 2005 Nov
Sood A, Barton DL, Bauer BA, Loprinzi CL. A critical review of complementary
therapies for cancer-related fatigue. Integr Cancer Ther. 2007 Mar;6(1):8-13.
Stanton AL, Ganz PA, Kwan L, Meyerowitz BE, Bower JE, Krupnick JL, Rowland JH,
Leedham B, Belin TR. Outcomes from the Moving Beyond Cancer
psychoeducational, randomized, controlled trial with breast cancer patients. J
Clin Oncol. 2005 Sep 1;23(25):6009-18.
Stone PC, Abdul-Wahab A, Gibson JS, Wright RJ, Andrews PL. Fatigue in cancer
patients is not related to changes in oxyhaemoglobin dissociation. Support Care
Cancer. 2005 Oct;13(10):854-8.
Straus DJ, Testa MA, Sarokhan BJ, Czuczman MS, Tulpule A, Turner RR, Riggs SA.
Quality-of-life and health benefits of early treatment of mild anemia: a
randomized trial of epoetin alfa in patients receiving chemotherapy for
hematologic malignancies. Cancer. 2006 Oct 15;107(8):1909-17.
Stricker CT, Drake D, Hoyer KA, Mock V. Evidence-based practice for fatigue
management in adults with cancer: exercise as an intervention. Oncol Nurs Forum.
2004 Sep 17;31(5):963-76. Review.
Thorsen L, Skovlund E, Stromme SB, Hornslien K, Dahl AA, Fossa SD.
Effectiveness of physical activity on cardiorespiratory fitness and
health-related quality of life in young and middle-aged cancer patients shortly
after chemotherapy. J Clin Oncol. 2005 Apr 1;23(10):2378-88.
Tsang KL, Carlson LE, Olson K. Pilot crossover trial of Reiki versus rest
for treating cancer-related fatigue. Integr Cancer Ther. 2007 Mar;6(1):25-35.
Watson T, Mock V. Exercise as an intervention for cancer-related fatigue.
Phys Ther. 2004 Aug;84(8):736-43. Review.
Yates P, Aranda S, Hargraves M, Mirolo B, Clavarino A, McLachlan S, Skerman H.
Randomized controlled trial of an educational intervention for managing fatigue
in women receiving adjuvant chemotherapy for early-stage breast cancer. J Clin
Oncol. 2005 Sep 1;23(25):6027-36.
[No authors listed] Epoetin alfa offers clinically significant improvements
in the quality of life
of anaemic cancer patients. Curr Med Res Opin. 2005;21 Suppl 2:S12-5.
[No authors listed] Treating anaemia with epoetin alfa is associated with
improvements in quality
of life in cancer patients receiving chemotherapy. Curr Med Res Opin. 2005;21
[No authors listed] Improvements in quality of life associated with epoetin
alfa treatment are
clinically, as well as statistically, significant. Curr Med Res Opin. 2005;21